Well I was up until 4am this morning with a new game Called Sword of the Stars. It's like a master of orion class game but with more emphasis on ship design and combat with small world system. It's pretty good and has a multi player component. The combats can be manually fought and have a low end home wordesk kind of look. They are phased RTS meaning the engine is turn based but the flow feels real time, kind of like a MMO. The tactile map is big and Bright, in the game I am playing there is lots of tech to research with dynamic tree's and linking and a ton of worlds to explore out to and colonize.
Anyway, if you have it and want to multi player lets give it a try.
If you want to check it out there is a demo
http://www.fileplanet.com/promotions/sots/
The tutorial in game is awful, just flip through the pdf manual in the directory and everything is pretty clear.